
Mitopure Barrier Cream
Envelop skin in a plush, protective barrier of moisture. This buttery, peptide-enhanced cream melts into skin, visibly reducing the appearance of wrinkles by 11% while increasing firmness and elasticity. Wake up to supple, 12% more hydrated skin.
50 mL / 1.7 fl oz
Complete your routine
TARGETED TOPICAL CARE


Unlock skin’s natural power to renew
A new standard in skin longevity, developed with patented Swiss biotechnology. Backed by 18+ years of research and validated by gold-standard human clinical trials — this is the Mitopure® difference.
- 30%
increase in skin renewal from Mitopure
- 93%
agree skin feels protected, stronger, and revitalized.
- 90%
agree skin tone looks brighter and more luminous.
- 86%
agree skin barrier feels strengthened and more resilient.
One Powerhouse Ingredient
| Comparison criteria | ![]() | ![]() Peptides | ![]() Retinol | ![]() Vitamin C |
|---|---|---|---|---|
| Activates mitophagy | ||||
| Targets cellular energy decline | Partial | Partial | ||
| Supports collagen assembly | ||||
| Protects against photodamage | Limited |
Mitopure revitalizes mitochondria
Age-related mitochondrial decline contributes to collagen loss and stalled skin renewal. Mitopure is clinically proven to:
Improve cellular energy production
Support collagen assembly
Reveal more youthful-looking skin
Key Ingredients
Our proprietary form of the postbiotic Urolithin A, Mitopure® is a longevity powerhouse that targets visible signs of aging by stimulating mitophagy and restoring mitochondrial energy. It’s formulated at its most potent topical concentration.





Swiss science
Lab tested
Cruelty free
100% Vegan
The Mitopure Routine
| The Mitopure Routine | ![]() | bestseller ![]() | ![]() Mitopure Barrier CreamNow 50 mL / 1.7 fl oz | ![]() |
|---|---|---|---|---|
| Step | Cleanse | Treat | Moisturize | Eye Treatment |
| Frequency | AM & PM | AM & PM | AM & PM | AM & PM |
| Instructions | Apply nickel-sized amount to damp skin, lather and rinse. | Gently press 2–3 drops into clean, dry skin. | 1–2 pumps on clean skin in upward sweeping motions. | Apply with mini cryo spoon. Gently tap around eye. |
| Shop now | Shop now | Shop now |
Customer Reviews
4.7/ 5
Based on 170 reviews
95%
Would recommend this product
- 581%
- 413%
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- 11%



















