Science Meets Luxury with Timeline’s Firming Serum

In the crowded world of skincare, most serums promise visible results, but rarely do they deliver. Timeline Skincare’s award-winning Firming Serum sets a new benchmark, harnessing the science of mitochondrial renewal to target skin aging at the cellular level.

Infused with high-performance bioactives, this luxe serum delivers visible radiance from the very first drop, while ongoing use continues to improve skin’s health at the cellular level.

Let’s break down the science.

Clinically Proven Efficacy
on Skin Aging Markers

Timeline’s Firming Serum isn’t just hype; rigorous clinical data back its benefits.
We conducted an 8-week randomized clinical trial in 36 healthy adults aged 40–65. Those using the Mitopure-containing serum saw statistically significant improvements in skin health, including:

• Reduced appearance of fine lines and wrinkles.†
• 23% improvement in skin hydration.†

† Based on an 8-week randomized controlled clinical trial of 36 healthy women aged 40 to 65 years. Morning and evening product application.

Consumer feedback mirrored the clinical results:*
• 90% agreed their skin “felt protected.”
• 80% said it looked more youthful.
• 77% noticed a tangible tightening effect.

This potent serum visibly tightens skin while supporting long-term skin renewal at the cellular level, with clinical trials and user studies to prove it.

*Based on a 3-week user trial of 30 healthy women aged 40 to 65 years. Morning and evening product application.

Next-Generation Longevity Ingredients

At the heart of this formula is 1% Mitopure® (Urolithin A), a patented, postbiotic molecule that rejuvenates skin through mitochondrial support. Mitopure’s Swiss technology is backed by over 18 years of research by physicians and PhDs, as well as numerous clinical trials, for proven, meaningful results. The active ingredient boosts the skin’s “energy supply,” while supporting healthy collagen assembly.

In addition to being infused with Mitopure, the serum delivers a sophisticated blend of bioactives to the skin, including:

• The proprietary complex of Mitopure, Niacinamide, and Trehalose ingredients known to re-energize cells while brightening and strengthening the skin barrier.
• Phytic acid, a gentle exfoliant that encourages cellular turnover.
• Red Algae, an antioxidant-rich marine botanical (also known as Chondrus Crispus) that supports lasting moisture retention.
• Caffeine, a stimulating antioxidant known to counteract puffiness in the skin.

A synergy of antioxidants and soothing botanicals rounds out the blend. This intelligent cocktail of clinically-trialed ingredients promotes skin longevity from the inside out, transforming your skin drop by drop.

Featherlight, Makeup-Ready Texture

Timeline’s Firming Serum has a milky, yet lightweight consistency that glides on smoothly and absorbs in seconds. It dries down cleanly, leaving no shine or tackiness, allowing it to layer perfectly under foundation or sunscreen.

Safe for All Skin,
Dermatologist-Tested Formula

The Serum, like all of Timeline's skincare products, was developed with sensitive skin in mind. We’ve conducted clinical trials to confirm it’s safe for all skin types, including sensitive, combination, and mature skin. Timeline’s study participants spanned a broad age range and included both women and men, demonstrating the formula’s gentle effectiveness across populations.**

Though powered by strong actives like Mitopure, and delivers retinoid-like results, the serum does not cause irritation or sensitization over time. It’s truly a high-performance product without the harsh side effects.**

**This product has been evaluated for skin irritation and sensitization potential in a Human Repeat Insult Patch Test (HRIPT) conducted on 113 healthy adult participants under controlled clinical conditions.

Mitopure Firming Serum

4.8 · 1454 reviews

Award-winning bioactive formula for renewal

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Complete the Routine

For best results, integrate the Firming Serum into the full Timeline skincare regimen. It pairs especially well with the Gentle Cleanser and the Resurfacing Exfoliator.

Here’s a step-by-step approach for optimal results:

1. Cleanse with the Gentle Cleanser: A cream-to-mousse formula that lifts impurities without drying the skin.

2. Exfoliate with the Resurfacing Exfoliator: A multi-acid treatment that improves skin texture and imparts an instant glow.

3. Follow up with the Firming Serum: Potent actives deeply penetrate to firm, hydrate and rejuvenate.

4. Moisturize with either the Dewy Cream or Barrier Cream as needed to seal in hydration and maintain skin barrier integrity.