Unlocking Cellular Energy: Secrets of Mitochondrial Health

Get ready to explore how Mitopure can seriously boost your mitochondria – those tiny powerhouses that keep you going strong.

Podcast

Biohacking with Brittany

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Brittany and Dr. Emily Werner dive into the world of Timeline Nutrition and the game-changing gem, Mitopure. Get ready to explore how this nutrient can seriously boost your mitochondria – those tiny powerhouses that keep you going strong.

Topics covered

- What is Mitopure

- How to support your mitochondria as you get older

- Who benefits from Mitopure?

- CoQ10 and the mitochondria

- What are the benefits of Mitopure

- How to know if your mitochondria are not performing as it should

- How long should you take Mitopure

- Mitopure skincare products and why they have it

- Misleading marketing in most supplements and skincare products

Transcript
Brittany Ford
Welcome to Biohacking with Brittany. Thank you for joining me, and welcome to the big, large, fun, birthday giveaway that I am doing. It just launched today, and you can win so many good things. I split this giveaway up into two prize boxes. Today is the first day that the first box is released and is up for grabs. Then tomorrow, the second box will be released, which has completely different products in it.
Brittany Ford
Each of these days features seven different brands in the health and wellness space, and you will be able to win all of the products. I will actually be sending the box to you directly myself. This is open to everybody. I'm really excited about this.
Brittany Ford
I wanted to do something fun for my birthday this year. I wanted to do something for my audience in general. I decided to do similar to my Christmas giveaway that I do, but a little different. This is just two different prizes, and the way that you enter is through the link in my bio on Instagram, on TikTok, it's being sent out on my newsletter, it's on my website, and it'll be in the show notes with this.
Brittany Ford
That is the only way to enter this time. Not through social media, not through tagging people or anything like that. It is solely through that link. Once you go into that link, you'll see extra ways to add in entries, which is really fun. If you share it, you can add a bunch of entries. If you do follow certain people, you can add entries and that type of thing. It's all in one place. When you enter, you actually enter for both days. So you will win either the day 1 box or the day 2 prize box. Good luck to everybody.
Brittany Ford
Honestly, it's a really large giveaway. Each prize box is valued at about $2,200 each. That includes a bunch of different products. The one that got released today, because today is day 1, is the one that features products from Timeline Nutrition, which I'm going to talk about. Glucokinase, Kineon or Kynon, BiOptimizers, Sensate, Prolong, and Zero app. Every day you're going to hear me talk about a different brand on the podcast and in my newsletter and on my blog.
Brittany Ford
I'm going to go through the products. I'm going to explain them to you. I'm going to tell you what you can win exactly from each. I really suggest you enter because honestly, this is such a good way to win and try a bunch of different biohacking and health and wellness products that you might not have even heard of or you've always wanted to try but have always been maybe too expensive or you maybe you just didn't justify buying it. But this way you get to win.
Brittany Ford
You actually would win from seven different products and seven different brands. It's pretty cool. Go check it out, it is live now. I am expecting a lot of people to enter, which I think is going to be really fun. The best part is, honestly, about these is I get to tell the person and I get to send them this box of goodies and these two people that are going to win. It's just so nice. It's so nice to be able to give stuff away, to be honest. Then they always message me on Instagram or send me an email and they're so thankful and they're so excited.
Brittany Ford
I just really love being able to do that. It's really special. I really encourage you to enter. Like I said, it's super easy through the link. Today, we are featuring Timeline Nutrition. You're going to hear my interview with their team. Timeline Nutrition is in the prize box for the first day. I love their berry powder. I add it to my yogurt with homemade granola and it's really good.
Brittany Ford
It has a compound in it called Urolithin A that is super great for the mitochondria in ourselves and it's really great for energy and longevity. So it's definitely one of these longevity supplements. A lot of big people really talk about Timeline Nutrition now, Dave Asprey, and people like that. It's definitely making waves, I would say, in the longevity space, which is why I wanted to include them in the giveaway because longevity in itself is becoming such a hot topic. There's so many people interested in it. I just love being able to provide something that can really benefit from everybody and benefit everybody. They actually just came out with a line of skincare as well, which is really cool.A
Brittany Ford
A lot of athletes love Timeline Nutrition for the energy, the strength, the endurance, just optimizing all of that. Again, just this Urolithin A, this new molecule that they found that a lot of people are lacking, which is leading to different age-related issues like I just talked about. You're going to hear all about this podcast today. Enjoy it. If you do want to try Timeline Nutrition outside of just entering my giveaway, you can do that. I will also put that link in the show notes. It's on my blog post that just came out today as well.
Brittany Ford
My discount code is Biohacking Brittany with Timeline Nutrition if you want to enter it and check it out. They have two different powders. They have the berry powder, the ginger powder, they have the capsules of the supplement, and then they also have the skincare line. So it's really exciting. They're doing a lot of good stuff. I actually had the pleasure of meeting them at the Biohacking Conference in June, which was really cool to be able to put a face to a name. I just really enjoyed it.
Brittany Ford
Like I said, I really am so excited to be able to provide this giveaway for you. Again, you could win $2,200 worth of prizes in one of the boxes each so it's almost $4,500 in total that you could win a biohacking gear. Who doesn't want to win all of that? I know I do. Enjoy this podcast episode and stay tuned for another one coming tomorrow. It's going to be an episode released every day for the next 12 days. Enjoy these little snippets and info on all of my favorite biohacking products and everything that I honestly use every day.
Brittany Ford
Welcome to Biohacking with Brittany. I am so excited that you are listening this week. This is a episode dedicated to the large and in charge giveaway that I am doing at the end of August for my birthday. I'm doing a two-day giveaway. There's going to be a bunch of different products in the biohacking and health optimization space that I am giving away to one lucky winner. Please enter if you have not entered or get ready to enter. It depends when this comes out.
Brittany Ford
But today, we are talking about mitochondria, we're talking about Timeline Nutrition, one of my favorite supplements that I've actually been using for quite a while now. It might even be a year, I don't know, but it's definitely quite a while. We're going to be exploring Mitopure by Timeline Nutrition, which is a revolutionary postbiotic nutrient that has shown promise in re-energizing our cells and combating age-related cellular decline. Dr. Emily Warner is joining us to talk about all things mitochondria. Welcome to the show.
Dr. Emily Warner
Thank you so much for having me.
Brittany Ford
I am so excited that you are here. For people who have never heard about Mitopure at all, how do you begin to explain this?
Dr. Emily Warner
It's a bit of a complicated story, but I usually start by asking if someone knows what mitochondria are or have heard of them.
Brittany Ford
Fair.
Dr. Emily Warner
I would say honestly 90 plus percent of people can pull from the depths of their brain to their high school biology class where they learned the classic mitochondria is the powerhouse of the cell phrase. I can start there and I'm like, okay, well, what does that mean, the powerhouse? Does that mean they are strength, they are muscle, or whatever, which they obviously have a role in both of those things? But I try to re-educate people that the mitochondria are where 90% of our body's energy are made.
Dr. Emily Warner
They are the primary site of this metabolic flexibility idea because they metabolize every macronutrient substrate that we put into our body. When it comes to how do we keep this powerhouse, the house that creates the power, how do we optimize it and keep it as healthy as we can for as long as we can? Because the research shows that the mitochondria optimize in our, I'm going to say 20s to 30s and then past that point, if you're not doing anything to help sustain the health of your mitochondria, they just slowly decline with age and with stress and with a lot of the turmoil that we put our bodies through.
Dr. Emily Warner
That's where optimizing them comes in, like taking different approaches, whether it be through diet, supplements or just general healthy eating patterns. Exercise has been shown to be one of the most beneficial ways to keep your mitochondria healthy. Then that's where Mitopure comes in. Do you want me to get into all of what Urolithin A, Mitopure, and all that?
Brittany Ford
Yeah. I think we can just focus on the mitochondria first because I think what you said is so true. A lot of people just know it as this cellular powerhouse. But how does it actually generate energy for our cells? We can get into how it declines over time, but how does it actually work? Even though we might understand that, do you know the mechanism behind it?
Dr. Emily Warner
Yeah. The mitochondria are the site in which… Like I said, all of the macronutrients we take in, so whether it be carbohydrates, fat, or protein, each of those nutrients in a way passes through the mitochondria and is transformed into adenosine triphosphate, which is ATP, our energy currency. There's really no way to explain in full detail on this kind of a podcast what that really takes because there's so many different steps and processes.
Dr. Emily Warner
There's different pathways through which we create ATP, and it also depends on which substrate is our starting fuel. There's a lot that goes into it. But the way the mitochondria come into play is that they are the location of where this is happening. They house the machinery that are necessary to convert the macronutrients into energy.
Brittany Ford
Yeah. No, that's a perfect way to describe it, a perfect overview. Obviously, it's much easier to describe if there's a graphic or a diagram or something that we can look at and understand it. I think that makes a lot of sense. Mitochondria, like you said, declines as we get older. It's hard when you hear that because obviously age is nothing that we can really do anything about. Obviously, time is going to just continue to go on. But what can we do, I guess, to really support our mitochondria as we get older so maybe it's somewhat functions like it does in our 20s?
Dr. Emily Warner
The ways in which our mitochondria are affected, there's modifiable factors and there's non-modifiable. The non-modifiable are like our sex, our aging, our genetics, Those kinds of things. The modifiables are where we can actually have quite a big impact, and that's where diet and exercise come into play.
Dr. Emily Warner
When it comes to exercise, there is decades of research showing the benefits of specifically cardiovascular and more endurance style exercise on mitochondrial biogenesis. A piece that I didn't really get into was this life cycle of a mitochondria. Within it, if I'm going to reduce it as much as I can, there's four-ish steps. Essentially what happens is as the body ages and incurs stress, the mitochondria make a decision of, okay, are we healthy enough to continue functioning as is? Do we need to break apart and combine with other broken pieces of dysfunctional mitochondria to create a new mitochondria so that we can function better? Or do we need to break apart and be taken away as waste? All of those pieces, if your audience has heard of fission, fusion, biogenesis, and mitophagy, those are the four pieces of it.
Dr. Emily Warner
Fission is that quality control mechanism of do we break apart or not? And if we do, what happens next? Fusion is exactly like it sounds, is the fusing of multiple dysfunctional mitochondria to create new mitochondria, which is the biogenesis piece. Genesis is to create. Then mitophagy is that clearing out of the waste. If a mitochondrion goes through fission and there isn't enough functional pieces of it left, what needs to happen is that waste needs to be removed because otherwise, if the dysfunctional mitochondria just sit around, it actually can cause damage to the mitochondrial DNA, increased reactive oxygen, species production, just a whole lot of cellular bad things. So we need that clearance process.
Brittany Ford
Yeah. In terms of that, that's where your product comes in. It helps with that cleanup process.
Dr. Emily Warner
Exactly. What our researchers found was this really amazing nutrient in pomegranates that they figured out triggers this mitophagy process. A lot of the thinking behind current research on diet and exercise for mitochondrial health is either in the biogenesis piece or it's in the mitophagy piece. When our researchers found this nutrient that can trigger mitophagy, it does it in the same way that the thought of intermittent fasting and exercise can trigger mitophagy. It's been the first bioactive nutrient that's been shown to do this.
Brittany Ford
Yeah. That's so exciting. It's so interesting how many products and supplements and all sorts of things are really coming out now focused on longevity and keeping optimal cellular function for longer seems to be such a hot topic for the last few years. It's really encouraging. Because, obviously, I don't think taking a supplement is a Band-Aid to anything. I still think like you said, you have to exercise, you have to eat right. There's all these lifestyle practices.
Brittany Ford
But it is exciting that we can reduce it to this one ingredient like Urolithin A that could really be impactful on a cellular level. Yeah, I'm just excited for it. Do you find like the people who... I guess maybe you have a few target audiences, but one of them is very concerned about aging and just wants to function better and maybe they're a bit older?
Dr. Emily Warner
Yeah, that's definitely a lot of those who have been interested in Mitopure. But we also get plenty of interest from those who are young and just trying to stay "young" for longer. There's also a lot of interest from athletes because the mitochondria have such a huge role in muscular health. If we can keep the mitochondria healthy for longer, we have research that shows we can improve muscular endurance and muscular strength. Definitely a lot of interest from multiple populations. When I get asked all the time, who is Mitopure for? Who can benefit from Mitopure? I'm like, "Well, anybody who has mitochondria can benefit. From it.
Brittany Ford
That's so interesting about the muscle. I was actually just talking to my husband about this. I really struggle to put muscle on, and he puts muscle on very easily, but he loses muscle very easily as well. It's just so interesting, and I wonder how taking an ingredient like this, if we both were to take it say, for a year or six months, something like that. I wonder the difference if it would really help me put on muscle or if it would just like,, I don't know, I'm just rambling here, but I just know that I struggle to actually put on muscle and strength. I just wonder if this is the type of thing that I should be taking daily.
Dr. Emily Warner
No, I totally get you. I'm a sports dietitian by trade, so that's totally my realm. I would be interested to hear a side-by-side comparison of yours and your husband's experience with Mitopour. It's a supplement that most people who anecdotally report how they feel. We have had people say that their workouts are better. They can go longer per workout or they recover faster between workouts. I think from that aspect, there could definitely be an impact on gaining muscle or maintaining muscle for that reason.
Dr. Emily Warner
It's not going to be something that... It's not protein. We do have a protein-included version protein Mitopure. The protein is actually what's adding the nutrients, what's adding the substrate necessary to build muscle. But whether your mitochondria are high functioning definitely plays a role in how well your body is just going to process things in general.
Brittany Ford
Yeah, for sure. It's interesting because I feel like when I think about my supplement stack, I don't actually take a lot of things that are geared specifically towards mitochondria. The one thing I do take is like CoQ-10, and I take the Ubiquinol form of it. I know that has an impact on mitochondria. I don't know if you know anything about that, but how do you think that that might compare to something like Urolithin A?
Dr. Emily Werner
I do. I actually just recently did a few talks comparing Urolithin A and CoQ10. A few deep dives into the research later. What we know about CoQ10 are a few things. Number one, its bioavailability is tough. It's low. The ubiquinol form is definitely the most bioavailable. But where the research still is lagging and what's the right dosage for certain effects.
Dr. Emily Werner
There's a good recent meta-analysis that basically concluded 200-300 milligrams of CoQ10 per day is what current research says is the best for the anti-inflammatory effects that CoQ10 can have. But as far as performance or anything specifically related to the mitochondria, the jury is still out on it.
Dr. Emily Werner
As far as how CoQ10 benefits the mitochondria or functions with the mitochondria, it actually isn't affecting the mitochondria organelle itself. CoQ10 is shuttling electrons within the energy chain. It's helping the mitochondria do their job better, but it's not doing anything to improve the lifespan of a mitochondria.
Dr. Emily Werner
If you think about it like a car. If your mitochondria are a car and you're putting miles and miles on it, and then you go and get it detailed. Yeah, it's going to look nicer and it might function better because it's all cleaned out and you've cleaned out the air ducts and you've done all the things, that's CoQ10. It's cleaning up what you already have.
Dr. Emily Werner
But no matter what, that car is going to continue to accrue miles. At some point, you are going to need to replace that car. That's where Urolithin A comes in, because CoQ10 won't replace the car, but Urolithin A will. It clears out that recycled, that needs-to-be-recycled waste to make room for biogenesis, which is new, fresh mitochondria that are higher functioning.
Dr. Emily Werner
CoQ10 is just polishing up what already exists, which definitely can be beneficial. There's no denying that helping them function better is great. But when you get to a certain point of function of a mitochondria or dysfunction for that matter, CoQ10, it's like putting lipstick on a pig.
Brittany Ford
That is very helpful to know, actually, because I didn't realize that. The reason I bring it up is so many women get recommended CoQ10 for egg quality and fertility and preconception and everything like that. That's the stage that I'm in right now. I'm taking a few different supplements from a company called Needed that specializes in those types of phases in a woman's life.
Brittany Ford
It's interesting because, as I'm sure you know, the eggs or the cells before the eggs, I guess, have the most mitochondria in them in the human body. I think it's 100,000 mitochondria per cell. It actually makes a difference when we look at mitochondria from a reproductive standpoint for women. I'm sure that your Urolithin A can actually really help women as well in this realm.
Dr. Emily Werner
Theoretically, yes. I have to be careful because I know since we don't have research in either pregnant or planning-to-be-pregnant populations. From a just safety blanket, I want to make sure to mention that. But in the same way that I would say people under 18 shouldn't necessarily consume this because we just don't know. We haven't done the research. That's just the practitioner that I am. But from a theoretical standpoint, yeah, absolutely. If I were in your position, I would very strongly consider Urolithin A.
Dr. Emily Werner
At the end of the day, because it's NSF-certified, we do know that it is a safe product. What is on the label is actually in the bottle, in the powder, whatever. That's why I use it with the athletes that I work with. At baseline, we know it's safe. Then efficacy beyond that, we know it's efficacious in very specific scenarios based off of the research that we've done in those scenarios. Then you just have to make the decision to extrapolate that out to your certain situation.
Brittany Ford
Yeah, absolutely. I mean, the field of reproductive longevity is growing, and there's a lot of people who are very interested in it for many different reasons that we don't have to get into. But it is really exciting when we can see an ingredient like this that comes out that says, "Hey, this might be able to help you." A lot of women actually really do need that support from a cellular level, for sure.
Brittany Ford
Are you planning to do any research in that realm in the future? Is that something you may explore?
Dr. Emily Werner
I'm not sure. That would be a question for our chief medical officer. I know that one thing we don't want to do is ever become a drug. It's not an area that we want to go down. That has some implications for what types of "clinical populations" that we attempt to do research in. I'm not saying it's against the possibilities or the hopes of what we have for Mitopure being just an overall holistic longevity, healthy nutrient. But whether or not we are able to utilize research funds to work in that specific population, I just don't know.
Brittany Ford
Yeah, for sure. No, that makes total sense. Other than reproductive longevity and just maybe longevity and athletes as well, what other benefits could people potentially get from this? Maybe just for the average person, if they were to take it daily for a few months, maybe a year, or something like that.
Dr. Emily Werner
For the average person, I would just say it depends on what ails them at the time. For a lot of people, it is fatigue, whether that be clinically diagnosed chronic fatigue or just subjective fatigue. I think that that's been one of the most common feedback that we get from people who try Mitopure. Myself included, when I first started taking it. The first thing that I noticed after a few weeks was just that I didn't need my midday nap anymore. I felt better. I didn't even realize it until later. I was like, "I haven't changed anything." I was like, "Oh, wait. I have started taking Mitopure. That's really interesting." Some other people report, like I was saying, better workouts, longer workouts, better recovery from those workouts, and that thing.
Dr. Emily Werner
Subjectively, we're working on publishing some of this subjective stuff, but I would say the primary realms in which we hear people's feedback is either in their exercise regimen, some benefit there, better sleep. We've had more energy throughout the day, and especially for people who spend a lot of time on their feet and they have jobs that require them to be very active, people have said that they just perform better throughout the day.
Brittany Ford
Nice. Yeah, I like that a lot. A lot of people really struggle with fatigue. Even myself. Earlier this week, I was like, "Why do I feel so tired?" Even for someone like me who's super into health and wellness, on those days where I feel really tired, it's not like I'm like, "Oh, I wonder what's happening with my mitochondria. Maybe it's sluggish." You know what I mean? It's such a far-away thought that it's not my first thing that I think of. I don't know, maybe it should be.
Brittany Ford
I guess the question is, how do you know if maybe your mitochondria is not performing really how you want it to? Would it just be fatigue or are there other symptoms that can come up?
Dr. Emily Werner
I mean, there's plenty of symptoms because the mitochondria really have a hand in just about everything that the body does. It's really hard to pinpoint specific symptoms that are related to mitochondrial dysfunction unless there is a clinically relevant testing done and there's a gene defect that shows mitochondrial defect, those kinds of things. But dysfunctional mitochondria are a part of just about every disease state that you can think of, from diabetes to chronic heart failure to neuropathies to just about everything.
Dr. Emily Werner
For the everyday person, I would say it's really hard to say that if you have this, you should take Mitopure. Like you said earlier, sometimes supplements get treated like Band-Aids. This isn't a Band-Aid. This is more of a lifetime maintenance option that you really don't know how it can benefit you until you try it.
Brittany Ford
Yeah, I completely agree. I'm glad you said that because it is really easy to just say, "Oh, take this one thing and it's going to fix everything." People want a quick fix. In my experience with the various health issues that I've had, there's no quick fixes for anything. It's really daily, healthy habits for a long period of time is what makes success. It would be the same with this. If you take it one day, that's great. But ideally, you're going to want to be taking it for longer.
Brittany Ford
If someone were to start on this and maybe their symptom is fatigue, how long do they need to be on it? Do you have to be on it for… I don't want to say for the rest of your life, but can you cycle on and off of it maybe just depending on how you feel? What are the general recommendations?
Dr. Emily Werner
The first part of that question, how long before you can expect to feel or see results? The endpoint of our outcomes in the research has been the two-month mark. That's when we can definitively say we've seen improvements in muscular strength and endurance. But I will say anecdotally, a lot of people report feeling better subjectively anywhere from two weeks to four weeks. It's just we just don't have hard clinical results to support that. But it's like, when are you going to feel better? Probably four weeks. When are you going to see results? Probably eight weeks, that thing.
Dr. Emily Werner
I love the question of, is this a lifelong thing? Right now, we just don't know because we're working on longitudinal studies of supplementation with this. But again, it's a relatively new nutrient. It's only been on the market since 2020. The research is much older than that. The research has been going on since about 2008, but we don't know.
Dr. Emily Werner
Cycling on and off, I hope we do some periodization study, especially because I work with athletes who have in-season and off-season and to get players to take pills in the off-season is a lot harder than during-season. I want us to be able to do some periodization. But right now, the short answer is we don't know.
Dr. Emily Werner
I have my theories that I do think that some cycling could be beneficial, because the way that the product works in general, because it takes so long to saturate the body and really see those effects in a meaningful way. Although the half-life of Urolithin A in the blood is only 24 hours, so that's why we say to try to take it at the same time every day so that you're just consistently trying to up your levels until you get to the point of saturation.
Dr. Emily Werner
I do think that saturation eventually lasts longer. If you start taking it and you're taking it for six months or so and then life happens and you're off it for a month, or you want to see how you feel or whatever, fine, go for it. Personally, I tried that, and I think I was off of it for almost two months and I didn't feel any different.
Dr. Emily Werner
Some people will say, "Well, that means it's not working at all." I was like, "Well, no. It actually just means that the effects are lasting." It's like if you look into the creatine research. Once you saturate the muscle with creatine, depending on the person, creatine stays saturated in the muscle for a month past supplementation. It really depends person to person.
Dr. Emily Werner
Again, to sum it up, based on the research, I have no idea if periodization matters. Based off of my own anecdotal report, I don't think periodization necessarily matters. If you want to take a month off, go for it. I would just say, get to a point of, you've been on it for long enough to feel comfortable doing that. Like with everything, just based off of how you feel.
Brittany Ford
Yeah, I like that a lot. I think you could track your symptoms as well and just make the decision for yourself, regardless of maybe what the research might say, which is what I do. Maybe there are points in your life where it's more useful and more helpful versus other points. It'll be exciting to watch that develop as you guys do more research and figure that out.
Brittany Ford
I take your powder. I have the berry powder. I really like it because I just add it to my yogurt and it actually just tastes so good. For me, it's a nice break from taking a supplement just as a capsule. I know you also have those. But I really like that you came out with that because I find I incorporate it more because of that.
Dr. Emily Werner
Hundred percent. Many people say that. I think it's so important, because as a dietitian, I want people to eat food. I don't want people to just take pills to get their health. The fact that we have food-based options… The berry powder, I personally love. I put it in oatmeal with a little bit of peanut butter. It's almost like a PB&J vibe. You're right. It does just taste really good.
Dr. Emily Werner
The ginger flavor is incredible too. It actually has 800 milligrams of ginger in it, which is basically a therapeutic level of ginger based on the research, so that added bonus. But having multiple options really allows for the versatility of people's preferences and travel and life, because when I'm on the road, I just take the pills. It's a lot easier than having to go find yogurt or oatmeal somewhere.
Brittany Ford
Yeah, I love that. Can you freeze the powder and then consume it at another time? I asked because I'm perfecting this healthy popsicle recipe. Sounds so ridiculous. Then the other day, I was like, "Oh, maybe I should put the Timeline Nutrition berry powder in the popsicle and just blend it with the coconut yogurt and it'll be fine. But then I don't know if it's going to impact how it acts in the body.
Dr. Emily Werner
You know what? That's a good question. I do know it's heat stable, but I don't know if it's cold stable. I will get back to you on that.
Brittany Ford
Okay, cool.
Dr. Emily Werner
Very interesting question. But theoretically, yeah, I think it would blend great with a yogurt in some sort of popsicle form. But to the actual metabolism of the nutrient, I don't know if it's affected by freezing. I will ask and get back to you.
Brittany Ford
Yeah, for sure. I think most things are more affected by heat than they are by cold. That denatures them. But I think, yeah, I guess we'll see what your team says.
Brittany Ford
Then you also came out with a line of skin products, which is so interesting. I haven't tried them. Why did you do this if we're focusing on mitochondria through a supplement for them and now you have a skincare line?
Dr. Emily Werner
I actually don't know whose idea it was first within the company. But basically, what they figured out was, okay, so the skin is arguably the largest or the second largest organ that we have. If you put muscle above skin, skin would be second largest. Your skin have plenty of mitochondria. What we found was that Urolithin A is actually absorbable through the skin. In addition to having the nutrition products where you are targeting the mitochondria from the inside out, creating a skincare line allows us to attack the mitochondria from the outside in because the skin experiences so much damage throughout life, photo damage and environmental, whether it be air quality, all those kinds of things do really affect our skin.
Dr. Emily Werner
The skincare line was created… I'll be honest, I use it every day. I love it. I bought it for my mother. I think it's wonderful. Unlike most, if not all… No, definitely not all other skincare companies, but unlike most high-end skincare companies, we actually have published research or are publishing research on our skincare products and its efficacy in photoaging and those intrinsic and extrinsic aging factors that we see presented in the skin.
Dr. Emily Werner
It's been really interesting to see that process come along and see the products develop because, again, they're very new, like you said. But personally, I love them. I've been using them for over a year, and I kid you not, I've never gotten more compliments on my skin.
Brittany Ford
Wow. Okay, that makes me want to try it. It was interesting when I was at the Biohacking conference, I met your team and they had this… I didn't do it, but my friend did it. They had this thing on an iPad and they basically took a photo of your skin, and I think it showed what age your skin was. It was so interesting that looking back, I was like, "Oh, I should have done that," because I would love to know what my skin is and how it's aging. But that's really cool.
Brittany Ford
It makes sense when you understand it from that perspective. I think it's interesting to see scientific companies that are rooted in science create skincare is such a different way to go about it than the majority of skincare companies that are out there that it's just lather this on top and now there's hydration. But it's like, okay, what's actually happening on a cellular level on your face when you're putting that on? You know what I mean?
Dr. Emily Werner
Hundred percent. It's so funny because our chief medical officer, he's a trained immunologist, he's a medical doctor, and a PhD. When we speak about the supplement space and then our nutrition products, when we started getting into the skin, he was like, "If you think the nutrition supplement research world is the Wild Wild West, then the skin is aliens. It is just outer space in terms of the regulations or lack thereof and the companies putting stuff out there. I mean, it's just so different than the consumable space. To your point, that's the biggest reason I love this company and willing to work with them is just because it's a science-first company and ethics is of highest priority always. That's why I put so much trust in what we produce.
Brittany Ford
Yeah, that's so interesting. I mean, this is a side tangent, but I listened to this podcast a while ago and it's called Science Vs, and it was science versus skincare. It explained how people get all of those stats on their skincare products that will say 97% increase in hydration or whatever stat that the company will say.
Brittany Ford
It's basically just they have a test population, they use the product every single day for three weeks, and then they send them a survey. People will be like, "Oh, yeah, sure. My skin feels more hydrated." Then they just take that 97% and then they slap it on the bottle and apparently that helps. Versus being, okay, clinically, this is actually shown and just much more rigorous testing than a simple email survey that people are low key paid to fill out. It's just ridiculous.
Dr. Emily Werner
No, 100%. I could go off on a whole tangent about the rules and restrictions, all of that behind just what we see on labels in general across food, across skincare, everything. You really don't know and you take the word on the label as Bible and just keep moving. It's just a Wild Wild West. It really is.
Brittany Ford
Yeah, it really is. You really have to have a sharp eye to understand products. It's the same with supplements too. It's not greenwashing. It's just natural. All of these words that people throw out there, it doesn't make any sense. You know what I mean? You have to read the ingredients.
Dr. Emily Werner
Hundred percent, because all of that is just marketing. That's what those our claims are marketing. I encourage people to even critique our products. If you really want to know, look into our website, look into what it takes for us to say clinically tested and approved and all of these things. Be critical, 100%.
Brittany Ford
Yeah. I think it's needed because both supplements and skincare is so saturated. There's so many products on the market. We really have to be skeptical and really look at it. Honestly, it's really hard to know what to get and what not to get. But it's great to have podcasts like this where we can dive in and be like, "Okay, this is how it actually works." It's just super useful for people.
Dr. Emily Werner
Yeah, absolutely. I think education and knowledge is power, 100%.
Brittany Ford
Exactly. If people want to connect with you and maybe read the research or follow you on social media, how can they do that?
Dr. Emily Werner
Sure. As far as the research goes, I would recommend they go to timeline.com. There are a lot of really great blogs as well as direct links to our published papers if people are so inclined.
Dr. Emily Werner
For me, I'm not huge on social media. I have a personal Instagram. It's @emilywerner, W-E-R-N-E-R, 34. I'm currently working on a website and whatnot. But like I said, my everyday job is a sports dietitian. I'm still trying to get into more of this space. But people are more than welcome to hit me up on Instagram. I'm also on LinkedIn. You can find me, Emily Werner. I would say those are probably the two primary ways.
Brittany Ford
Amazing. I will put all of that in the show notes and on my website so people can find you and connect with Timeline Nutrition and maybe check out their products and their skincare line. Thank you so much for coming on the podcast. This is great. I know my audience definitely got a lot out of it.
Dr. Emily Werner
You're welcome and happy upcoming birthday.
Brittany Ford
Thank you.
Brittany Ford
Thanks for listening to another episode of Biohacking with Brittany. If you're interested in finding the show notes or the sponsors for this episode, you can do so on my website, which is biohackingbrittany.com. Remember to follow me on Instagram where I'm most active. My handle is @biohackingbrittany. If you're interested in working together and you want to email me directly, you can do that. My email is info@biohackingbrittany.com. I look forward to hearing from you and having you tune in next week.

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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. References: *Nutrition studies: 500mg Mitopure® have been shown to (1) induce gene expression related to mitochondria function and metabolism and (2) increase the strength of the hamstring leg muscle in measures of knee extension and flexion in overweight 40-65 year olds. Data from two randomized double-blind placebo-controlled human clinical trials. **Nutrition NOURISH Study: 500mg Mitopure® have been shown to deliver at least 6 times higher Urolithin A plasma levels over 24 hours (area under the curve) than 8 ounces (240ml) of pomegranate juice in a randomized human clinical trial.

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