Fueling Longevity: Andréane’s Work with Urolithin A

Go behind the scenes with Andréane, Timeline’s Lab Manager, as she explores the science and real-world impact of Urolithin A.

Andreane in the mountains

What to know

  • Andréane Mégane Fouassier leads lab operations at Timeline, helping advance research on Urolithin A and mitochondrial health.

  • Every day, she sees the real-time effects of Urolithin A in cell cultures and tissue models, reinforcing its powerful role in cellular energy and renewal.

  • Mitopure®, Timeline’s Urolithin A formulation, is clinically proven to improve muscle strength, boost energy, and support skin health.

  • Andréane is especially excited about exploring Urolithin A’s potential in brain and gut health — the next frontiers of longevity science.

At Timeline, science isn’t confined to theory. It’s tested, observed, and refined in the lab every day. That’s where Andréane Mégane Fouassier comes in. As Lab Manager on the Science Team, she plays a pivotal role in driving forward the research behind Urolithin A and unlocking its full potential as a longevity molecule.

From designing experiments to managing lab operations and encouraging the spirit of curiosity, Andréane works at the intersection of research and innovation. Her goal? To make sure the discoveries being made in the lab translate into real-world impact. And she’s already seeing it happen.

quote from andreane

Why Urolithin A Stands Out

In a world buzzing with so-called “longevity molecules,” Andréane believes Urolithin A is in a category of its own.

For Andréane, Urolithin A is special. She shares, "I am really working closely and actively with this compound, and I know the real and concrete potential of it. We also have our clinical study confirming what I am seeing in the lab, and that is incredible.”

andreane quote

She’s referring to our clinical trials showcasing how Mitopure® can help support muscle health.

By triggering a cellular recycling process called mitophagy, Mitopure helps to replace old, worn-out mitochondria with newer, better-functioning ones. [1]Clinical trials with Mitopure have shown its ability to significantly:

  • Increase cellular energy[2]
  • Improve muscle strength[3]
  • Promote cellular renewal
  • Support healthy aging

Additionally, topical application of Mitopure boosts the health of our skin by targeting the biological and environmental factors that contribute to skin aging.[4]

She also points to mitochondria’s underrated importance. “Most people don’t realize mitochondria do so much more than power our cells. They regulate cell death, influence immunity, control metabolism, and they even have their own DNA!”

mitopure

When asked what’s next for Mitopure, she’s particularly intrigued by the gut-brain connection. “Urolithin A’s effects on muscle and skin are well studied, but I think gut and brain health will be important frontiers. We’re learning all the time.”

Mitopure Softgels
Mitopure Softgels
Bestseller

4.4 · 3356 reviews

The simplest form of Mitopure

Buy now

A Passion for Mitochondria, Sparked Early

Every member of Timeline’s scientific team has dedicated their academic and professional careers to advancing expertise in mitochondrial and cellular health.

For Andréane, her journey to Timeline started in Lyon, France, where she earned a double bachelor’s degree in Biology, Biochemistry & Biotechnology, and Genetics. She went on to work in a research lab led by one of the pioneers in mitochondria and metabolism science, an experience that shaped her scientific path.

andreane quote

This passion made Timeline a natural fit. “I’m proud to be part of a company that not only advances scientific understanding but also delivers real-world impact. We have a product on the market that reflects the concrete results of our research.”

Science Meets the Everyday

Outside of the lab, Andréane is focused on putting what she’s learned into practice — even if she doesn’t claim perfection.

“I try to give my body the nutrition and movement it needs, because I know how much it matters. People don’t always realize how deeply it affects not just physical but mental health too.”

And when she’s not working? She’s either surrounded by loved ones or on her own, recharging by the lake with a good dose of nature and quiet.

andreane quote

The Takeaway: Science That Moves Us Forward

Andréane’s story is a powerful reminder that breakthrough science isn’t just happening in journals or conferences. It’s unfolding in the lab, every day, through the hands of dedicated researchers like her. At Timeline, it’s this kind of passion, persistence, and curiosity that fuels our mission to turn cutting-edge discoveries into real, measurable benefits for health and longevity.

Authors

Jen Scheinman, MS, RDN, CDN

Written by

Senior Manager of Nutrition Affairs

Julie Faitg, PhD

Reviewed by

Lead Regulatory Affairs & Scientific Manager Alliances at Timeline

References

  1. Andreux, P.A., Blanco-Bose, W., Ryu, D. et al. The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans. Nat Metab 1, 595–603 (2019). https://doi.org/10.1038/s42255-019-0073-4 (https://www.google.com/url?q=https://doi.org/10.1038/s42255-019-0073-4&sa=D&source=docs&ust=1754538315087918&usg=AOvVaw2OLQnJqrXrtL6OzhN0Pf24)

  2. Andreux, P.A., Blanco-Bose, W., Ryu, D. et al. The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans. Nat Metab 1, 595–603 (2019). https://doi.org/10.1038/s42255-019-0073-4 (https://www.google.com/url?q=https://doi.org/10.1038/s42255-019-0073-4&sa=D&source=docs&ust=1755099975309981&usg=AOvVaw2p5NAH59WTlLSBv4kd1ged)

  3. Andreux, P.A., Blanco-Bose, W., Ryu, D. et al. The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans. Nat Metab 1, 595–603 (2019). https://doi.org/10.1038/s42255-019-0073-4 (https://www.google.com/url?q=https://doi.org/10.1038/s42255-019-0073-4&sa=D&source=docs&ust=1755099975309981&usg=AOvVaw2p5NAH59WTlLSBv4kd1ged)

  4. Topical application of Urolithin A slows intrinsic skin aging and protects from UVB-mediated photodamage: Findings from Randomized Clinical Trials
    D D’Amico, AM Fouassier, J Faitg, N Hennighausen, M Brandt, D Konstantopoulos, C Rinsch, A Singh
    medRxiv 2023.06.16.23291378; doi: https://doi.org/10.1101/2023.06.16.23291378 (https://www.google.com/url?q=https://doi.org/10.1101/2023.06.16.23291378&sa=D&source=docs&ust=1754538315094434&usg=AOvVaw1ustTNl6h2gPhP6wP_itod)

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. References: *Nutrition studies: 500mg Mitopure® have been shown to (1) induce gene expression related to mitochondria function and metabolism and (2) increase the strength of the hamstring leg muscle in measures of knee extension and flexion in overweight 40-65 year olds. Data from two randomized double-blind placebo-controlled human clinical trials. **Nutrition NOURISH Study: 500mg Mitopure® have been shown to deliver at least 6 times higher Urolithin A plasma levels over 24 hours (area under the curve) than 8 ounces (240ml) of pomegranate juice in a randomized human clinical trial.

© 2025