Boosting Physical Strength as We Age

Prof. Stuart Phillips is the director of the Physical Activity Centre of Excellence (PACE) at the Department of Kinesiology at McMaster University.


Live Long and Master Aging


A key pillar of human longevity is our ability to remain physically strong and active as we age. Frailty is an all-too-familiar downside of growing old. But there is much we can do to slow down and even reverse the process that leads to the weakening of our limbs. In this episode of the Live Long and Master Aging (LLAMA) podcast, we delve into the latest clinical discoveries that could help us stay strong and vital for much longer. Prof. Stuart Phillips, director of the Physical Activity Centre of Excellence (PACE) at the Department of Kinesiology at McMaster University, Hamilton, Ontario, explains how laboratory research into mitochondrial health is being applied to human physiology. Dr. Phillips is a member of the advisory board of Amazentis, the Swiss life science company, which has partnered with the LLAMA podcast to produce this episode.

Topics covered

  • PACE – a community access exercise facility for special populations over the age of 55
  • The impact a period of muscular disuse has on the body
  • Why Covid has had such a marked effect on older people through inactivity

“Most clinicians would acknowledge that a bout of physical inactivity, bedrest or illness is a watershed moment for older people.”

  • The classic image of the older, retired person and why the notion of aging is associated with a decline in our physical functions is being challenged.
  • Pursuing a goal of aging as healthily as we can for as long as we can.
  • Understanding the phenomenon of Sarcopenia

“I don’t think that in your lifetime or my lifetime, we’re going to see the magic, so-called, anti-aging pill."

  • The condition known as frailty.
  • Ten thousand steps per day – why that number?
  • Type II diabetes and psychical activity.
  • Working with Amazentis to explore the benefits of Mitopure, a pure form of urolithin A, in humans.

“I’ve been really impressed with the scientific trajectory that the company (Amazenitis) has taken. It’s backed by a lot of good research.”

  • Making the connection between research in laboratory animals and humans.

“We’re actually eager to conduct some research with this compound because we think that the upside of it for aging people is tremendous.”

  • Lifestyles that give meaning to life.
  • The protein question – how much and what kind?
  • The declining immune system with aging. Why are exercise king and nutrition queen?

“Being physically active is the forgiver of a lot of sins.”

  • Is there a recipe for good exercise?
  • Why do we run marathons?
  • The power of walking
  • Spreading the message of healthy aging through social media

“If you’re up for a walk seven days a week, my bet is that you’re in pretty darn good shape.” The Live Long and Master Aging podcast shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Knowledge is power

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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. References: *Nutrition studies: 500mg Mitopure® have been shown to (1) induce gene expression related to mitochondria function and metabolism and (2) increase the strength of the hamstring leg muscle in measures of knee extension and flexion in overweight 40-65 year olds. Data from two randomized double-blind placebo-controlled human clinical trials. **Nutrition NOURISH Study: 500mg Mitopure® have been shown to deliver at least 6 times higher Urolithin A plasma levels over 24 hours (area under the curve) than 8 ounces (240ml) of pomegranate juice in a randomized human clinical trial.

© 2024
© 2024