
#1
Urolithin A Brand

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Optimize Longevity, Inside and Out
Support healthy aging, holistically, with patented mitochondrial science. Backed by 18+ years of research, validated by results.
MD-formulated with Mitopure®: a breakthrough longevity active
Addresses signs of aging at the cellular level by renewing mitochondria
Clinically proven supplements + topicals deliver full-body impact
#1
Urolithin A Brand
18⁺
Years of research
In collaboration with the Swiss Federal Institute of Technology de Lausanne (EPFL)
25
Human clinical trials
Completed and ongoing gold-standard clinical trials on nutrition and skincare involving over 900 participants
500⁺
Scientists have extensively explored Urolithin A’s effectiveness on health and patented the bioactive into Mitopure®
80
Patents
Our proprietary ingredient Mitopure® is protected under 80 patents
Your cells lose power with age
Mitochondria — the engines of your cells — generates the energy that your body needs.
In your 30s, mitochondria declines, causing signs of aging to surface. Over time, they become old, damaged and build up, draining cellular energy.
Rise in harmful molecules & senescent cells
Insufficient energy supply
Reduction in cellular & muscle health
Impacted skin quality
Rise in harmful molecules & senescent cells
Insufficient energy supply
Reduction in cellular & muscle health
Impacted skin quality
Rejuvenates mitochondria
Mitopure® is clinically proven to induce a crucial recycling process called mitophagy, which clears out and renews damaged mitochondria, redefining how cells age. When cells have more energy, organs can function optimally, supporting health span and longevity.

Inside and outside
Our patented form of Urolithin A, , supports healthy aging at the cellular level for a difference you’ll see and feel. Research shows that a dual approach best supports mitochondrial function inside and out.
Supplements
When taken orally, Mitopure® supports cellular energy systemically by targeting mitochondria across organs and tissues.
Topicals
As the body’s visible biomarker of aging, skin benefits most from local application and targeted delivery through Mitopure® topicals.
Together
By targeting cellular renewal and supporting mitochondrial function holistically, Timeline’s solutions optimize healthspan beyond the surface.
Compare us to other
One Powerhouse Ingredient
| Comparison criteria | ![]() | ![]() Peptides | ![]() Retinol | ![]() Vitamin C |
|---|---|---|---|---|
| Activates mitophagy | ||||
| Targets cellular energy decline | Partial | Partial | ||
| Supports collagen assembly | ||||
| Protects against photodamage | Limited |

After

Before

Results from
Mitopure Resurfacing Exfoliator

After

Before

Results from
Mitopure Firming Serum
2.1x increase in skin cell renewal
After 15 days vs. baseline
agree skin immediately looks smoother
agree it resurfaces skin, enhancing radiance
agree it effectively refines texture, evens tone & skin looks visibly renewed
agree that it brightens complexion

Mitopure Inside Out Set
Two clinically proven approaches to healthy aging, available in one complete routine. Save $144 when you pair longevity supplements with targeted topicals.
What's included
Inside and Out Set includes
| Inside and Out Set includes | Sugar Free ![]() | bestseller ![]() | ![]() |
|---|---|---|---|
| Benefits | Increases cellular energy & muscle strength | Gently resurfaces, improves skin texture & supports cellular renewal | Supports skin healthspan, reduces wrinkle visibility & increases skin hydration. |
| Key Ingredients | Mitopure® (Urolithin A) | Mitopure®, Plant-Based Salicylic Acid, Mandelic Acid & Lactic Acid | Mitopure®, Niacinamide, Phytic Acid, Multi-Layer Hydration System & Peptide Complex |
| How to use | Take two gummies daily for the recommended dose (500mg) | After cleansing, dispense a nickel-sized amount and sweep across the face and neck. Do not rinse. | Gently press 2-3 drops into clean, dry skin morning & night |
Swiss Science
Dermatologist approved
Senstive skin safe
Gold-standard clinical trials
Fragrance & Colorant Free
Cruelty free
Recommended byDoctors, Dermatologists, & Experts
Frequently Asked Questions
Have more questions? Visit our Help Center or inquire at care@timeline.com









