The Day CreamRefill

Redensifies the skin to leave it looking intensely revitalized, rejuvenated and resilient. Clinically proven to boost skin hydration and dramatically reduce the appearance of wrinkle depth after 2 weeks of use. Overall skin quality, texture and radiance are visibly improved. Leaves the skin soft and with a silky feeling. Powered by Mitopure®. For all skin types and genders. Includes one 50mL pre-filled insert. Permanent glass outer packaging not included.

HSA/FSA eligible with TrueMed · Get pre-qualified

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  • Revitalizes

  • Redensifies

  • Hydrates

  • Brightens

The Day Cream Refill
The Day Cream Refill
The Day Cream Refill
The Day Cream Refill
The Day Cream Refill
The Day Cream Refill
The Day Cream Refill

Looking for the whole product?

If this is your first time purchasing The Day Cream, shop the full set including permanent refillable packaging.

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Woman using the Day Cream
Mitopure (Urolithin A) Molecule

The first and only bioactive clinically proven to re‑energize cells

Building on prior research, we have now demonstrated that when applied topically our breakthrough ingredient supports cellular renewal from within the skin cells, for youthful looking skin, full of life and energy.

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The proven benefits of the Day Cream

The Day Cream has been proven to revitalize, redensify, hydrate and brighten skin’s appearance so that your skin can look full of life, like the way you feel inside!



Re-energizes the skin leaving it dramatically revitalized



Significantly reduces the appearance of fine lines and wrinkles for a firmer, dense-looking skin texture



Locks-in moisture for a well-hydrated skin



Powers-up cells renewal for a brighter, more even-looking looking skin

The Day Cream

Clinical results validated by users

We rigorously study the impact of our products to make sure they are both effective and loved by the people using them. Based on a 3-week user trial of 30 healthy women aged 40 to 65 years.

  • 87%

    agree skin’s texture looks and feels redensified and with more volume

  • 100%

    agree skin looks more radiant, brighter and glowing with health

  • 100%

    agree skin feels immediately hydrated, nourished and supple

  • 90%

    agree skin feels protected, stronger and revitalized

  • 83%

    agree skin looks more youthful and visibly renewed

People smiling while holding The Day Cream

High-performing, science-selected, sustainably sourced ingredients

Our exclusive, patented ingredient Mitopure® has been placed alongside carefully selected skin bioactives, designed to help the skin protect itself from external aging triggers, while enhancing intrinsic cell renewal.

How to apply

  • Step 1

    Apply in the morning, by itself or after the Serum. Dispense the desired amount onto clean fingertips. Then smooth over the face, neck and décolleté. Start from the center of your face outward.

  • Step 2

    In upward sweeping motions, massage the cream along your jawline. Sweep from your nose to your ears and across your forehead and massage cream over the cheeks to your temples.

  • Step 3

    Apply from the base of the neck to the tip of the chin. Take any excess cream and massage over the décolleté.

How we package our products matter

We are very mindful of our environmental impact and committed to providing packaging that’s as durable and sustainable as possible.

  • Airless design

    Our airless packaging increases the product lifespan reducing the need for preservatives. Plus, it ensures you get every last drop of our product.

  • Refillable packaging

    We reduce waste with a refillable system. After your first purchase, you will have the ability to keep most of the packaging components and just buy the refills.

  • Sustainable materials

    The glass and plastic we use in our packaging are 100% recyclable. Our cartons are made of FSC-certified, biodegradable paper.

The Day Cream refillable packaging

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Have more questions? Visit our Help Center or inquire at

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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. References: *Nutrition studies: 500mg Mitopure® have been shown to (1) induce gene expression related to mitochondria function and metabolism and (2) increase the strength of the hamstring leg muscle in measures of knee extension and flexion in overweight 40-65 year olds. Data from two randomized double-blind placebo-controlled human clinical trials. **Nutrition NOURISH Study: 500mg Mitopure® have been shown to deliver at least 6 times higher Urolithin A plasma levels over 24 hours (area under the curve) than 8 ounces (240ml) of pomegranate juice in a randomized human clinical trial.

© 2024
© 2024